DiffGraph: An R package for identifying gene network rewiring using differential graphical models.

Summary We develop DiffGraph, anRpackage that integrates four influential differential graphical models for identifying gene network rewiring under two different conditions from gene expression data. The input and output of different models are packaged in the same format, making it convenient for users to comparedifferent models using a wide range of datasets and carry out follow-up analysis. Furthermore, the inferreddifferential networks can be visualized both non-interactively and interactively. The package is useful foridentifying gene network rewiring from input datasets, comparing the predictions of different methods, andvisualizing the results. Availability and Implementation The package is available at https://github.com/Zhangxf-ccnu/DiffGraph. Contact [email protected]. Supplementary information Supplementary data are available at Bioinformatics online.